Tumour stem cells in breast cancer
Tumour stem cells (CSCs) are a self-renewing population that plays important roles in tumour initiation, recurrence, and metastasis. Although the medical literature is extensive, problems with CSC identification and cancer therapy remain. This review provides the main mechanisms of CSC action in bre...
| Published in: | International journal of molecular sciences Vol. 23, № 9. P. 5058 (1-21) |
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| Main Author: | |
| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001001441 Перейти в каталог НБ ТГУ |
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| 100 | 1 | |a Ibragimova, Marina K. |9 101505 | |
| 245 | 1 | 0 | |a Tumour stem cells in breast cancer |c M. K. Ibragimova, M. M. Tsyganov, N. V. Litviakov |
| 336 | |a Текст | ||
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| 504 | |a Библиогр.: 184 назв. | ||
| 520 | 3 | |a Tumour stem cells (CSCs) are a self-renewing population that plays important roles in tumour initiation, recurrence, and metastasis. Although the medical literature is extensive, problems with CSC identification and cancer therapy remain. This review provides the main mechanisms of CSC action in breast cancer (BC): CSC markers and signalling pathways, heterogeneity, plasticity, and ecological behaviour. The dynamic heterogeneity of CSCs and the dynamic transitions of CSC- non-CSCs and their significance for metastasis are considered. | |
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| 655 | 4 | |a статьи в журналах |9 885195 | |
| 700 | 1 | |a Tsyganov, Matvey M. |9 219371 | |
| 700 | 1 | |a Litvyakov, Nicolay V. |9 101564 | |
| 773 | 0 | |t International journal of molecular sciences |d 2022 |g Vol. 23, № 9. P. 5058 (1-21) |x 1661-6596 | |
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