Estimation of the regenerative potential of para-tyrosol in the model of testicular insufficiency caused by damage to spermatogonial stem cells
The regenerative properties of p-tyrosol were investigated in a model of testicular insufficiency caused by a toxic effect on spermatogonial stem cells (single administration of paclitaxel in the maximum tolerable dose). Against the background of p-tyrosol administration, we observed an increase in...
| Published in: | Bulletin of experimental biology and medicine Vol. 172, № 5. P. 632-636 |
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| Other Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001002445 Перейти в каталог НБ ТГУ |
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| 245 | 1 | 0 | |a Estimation of the regenerative potential of para-tyrosol in the model of testicular insufficiency caused by damage to spermatogonial stem cells |c T. G. Borovskaya, V. A. Grigor'eva, Yu. A. Shchemerova [et al.] |
| 336 | |a Текст | ||
| 337 | |a электронный | ||
| 504 | |a Библиогр.: 15 назв. | ||
| 520 | 3 | |a The regenerative properties of p-tyrosol were investigated in a model of testicular insufficiency caused by a toxic effect on spermatogonial stem cells (single administration of paclitaxel in the maximum tolerable dose). Against the background of p-tyrosol administration, we observed an increase in the number of normal spermatogonia and Sertoli cells, stimulation of spermatogenesis, and renewal of the spermatogenic tissue. The treatment with p-tyrosol also led to a decrease in DNA damage in cells of the testicular tissue. These changes were accompanied by a decrease in the level of free radicals, an increase in antioxidant protection, and normalization of the redox potential. | |
| 653 | |a пара-тирозол | ||
| 653 | |a паклитаксел | ||
| 653 | |a сперматогонии | ||
| 653 | |a крысы | ||
| 655 | 4 | |a статьи в журналах |9 886847 | |
| 700 | 1 | |a Borovskaya, T. G. |9 886846 | |
| 700 | 1 | |a Grigoreva, V. A |9 886848 | |
| 700 | 1 | |a Shchemerova, Yu. A. |9 886849 | |
| 700 | 1 | |a Kamalova, S. I. |9 886850 | |
| 700 | 1 | |a Vychuzhanina, A. V. |9 886851 | |
| 700 | 1 | |a Krivova, Natalya A. |9 423625 | |
| 700 | 1 | |a Zaeva, O. B. |9 886852 | |
| 700 | 1 | |a Goldberg, Victor E. |9 886853 | |
| 700 | 1 | |a Dyga, Alexander M. |9 886854 | |
| 773 | 0 | |t Bulletin of experimental biology and medicine |d 2022 |g Vol. 172, № 5. P. 632-636 |x 0007-4888 | |
| 852 | 4 | |a RU-ToGU | |
| 856 | 4 | |u http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001002445 | |
| 856 | |y Перейти в каталог НБ ТГУ |u https://koha.lib.tsu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=1002445 | ||
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