Mechanisms of the effects of short-term inhalations of Xe and O2 gas mixture in the rehabilitation of post-covid ventilation failure
The article presents a theoretical rationale and a clinical case of relief of post-COVID ventilation failure by inhalation of Xe and O-2 gas mixture. Pneumonitis of coronavirus etiology transforms saturated phospholipids of surfactant into a solid-ordered phase, which disrupts surface tension, alveo...
| Published in: | Bulletin of experimental biology and medicine Vol. 172, № 3. P. 364-367 |
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| Other Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001004091 Перейти в каталог НБ ТГУ |
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| 245 | 1 | 0 | |a Mechanisms of the effects of short-term inhalations of Xe and O2 gas mixture in the rehabilitation of post-covid ventilation failure |c V. V. Udut, S. A. Naumov, E. V. Udut [et al.] |
| 336 | |a Текст | ||
| 337 | |a электронный | ||
| 504 | |a Библиогр.: 15 назв. | ||
| 520 | 3 | |a The article presents a theoretical rationale and a clinical case of relief of post-COVID ventilation failure by inhalation of Xe and O-2 gas mixture. Pneumonitis of coronavirus etiology transforms saturated phospholipids of surfactant into a solid-ordered phase, which disrupts surface tension, alveolar pneumatization, and alveolar-capillary gas exchange. Using molecular modeling (B3LYP/lanl2dz; GAUSSIAN09), we demonstrated that Xe atom due to the van der Waals dispersion interaction increases the distance between the phospholipid acyl chains providing a phase transition from the solid-ordered to liquid phase and restored the surface-active monolayer surfactant film. A clinical case confirmed that short-term inhalations of the Xe and O-2 gas mixture relieved manifestations of ventilation insufficiency and increased SpO(2) and pneumatization of the terminal parts of the lungs. | |
| 653 | |a постковидные осложнения | ||
| 653 | |a легочный сурфактант | ||
| 653 | |a дипальмитоилфосфатидилхолин | ||
| 653 | |a молекулярный электростатический потенциал | ||
| 653 | |a ингаляции газовой смесью ксенона и кислорода | ||
| 655 | 4 | |a статьи в журналах |9 890006 | |
| 700 | 1 | |a Udut, Vladimir V. |9 404503 | |
| 700 | 1 | |a Naumov, Sergei Alexandrovich |9 804042 | |
| 700 | 1 | |a Udut, Elena V. |9 423460 | |
| 700 | 1 | |a Naumov, Sergei Sergeevich |9 804045 | |
| 700 | 1 | |a Evtushenko, Diana Nikolaevna |9 804043 | |
| 700 | 1 | |a Chumakova, O. N. |9 890007 | |
| 700 | 1 | |a Zyuzkov, Gleb N. |9 804046 | |
| 773 | 0 | |t Bulletin of experimental biology and medicine |d 2022 |g Vol. 172, № 3. P. 364-367 |x 0007-4888 | |
| 852 | 4 | |a RU-ToGU | |
| 856 | 4 | |u http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001004091 | |
| 856 | |y Перейти в каталог НБ ТГУ |u https://koha.lib.tsu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=1004091 | ||
| 908 | |a статья | ||
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