Создание системы доставки лекарства ZIF-8/новокаин и исследование кинетики высвобождения лекарственного компонента при различных pH
In this work, the authors consider the development of a drug delivery system (DDS) based on the ZIF-8 metal–organic framework and the non-steroidal anti-inflammatory drug novocaine. The synthesis of the delivery system is carried out in two ways: a one-pot synthesis method (the introduction of novoc...
| Published in: | Перспективы развития фундаментальных наук. Т. 2 : сборник научных трудов XIX Международной конференции студентов, аспирантов и молодых ученых, 26-29 апреля 2022 г. Т. 2 : Химия. С. 190-193 |
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| Format: | Book Chapter |
| Language: | Russian |
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| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001007149 |
| Summary: | In this work, the authors consider the development of a drug delivery system (DDS) based on the ZIF-8 metal–organic framework and the non-steroidal anti-inflammatory drug novocaine. The synthesis of the delivery system is carried out in two ways: a one-pot synthesis method (the introduction of novocaine during the hydrothermal synthesis of ZIF-8) and a two-pot method (impregnation of the carrier with a solution of novocaine). Additionally, the authors consider the kinetics of novocaine release under various conditions (pH, temperature, ionic strength, and the presence of foreign ions Na+ and Cl-). |
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| Bibliography: | Библиогр.: 5 назв. |
| ISBN: | 9785438710837 9785438710813 |