Reaction pathway and kinetic study of 4,5-dihydroxyimidazolidine-2-thione synthesis by HPLC and NMR
Process of 4,5-dihydroxyimidazolidine-2-thione (DHIT) synthesis from thiourea and glyoxal is studied. Formation of imidazole-2-thiones and 4,5-dihydroxyimidazolidin-2-one as byproducts is confirmed by NMR. The kinetics of the scalable DHIT synthesis process is studied by HPLC, and the kinetic parame...
| Published in: | Heterocycles Vol. 104, № 11. P. 1954-1965 |
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| Other Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001008788 Перейти в каталог НБ ТГУ |