Solubility in pharmaceutical chemistry
This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify...
| Другие авторы: | , |
|---|---|
| Формат: | Электронная книга |
| Язык: | English |
| Публикация: |
Berlin ; Boston
Walter de Gruyter GmbH,
[2020]
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| Предметы: | |
| Online-ссылка: | EBSCOhost Перейти в каталог НБ ТГУ |
| LEADER | 03760cam a2200637 i 4500 | ||
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| 001 | koha001011435 | ||
| 003 | OCoLC | ||
| 005 | 20250222065848.0 | ||
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| 008 | 191221s2020 gw fo z000 0 eng d | ||
| 035 | |a koha001011435 | ||
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| 020 | |a 3110558882 |q (electronic book) | ||
| 020 | |a 9783110559835 |q (electronic book) | ||
| 020 | |a 3110559838 |q (electronic book) | ||
| 020 | |a 9783110558883 |q (electronic bk.) | ||
| 024 | 7 | |a 10.1515/9783110559835 |2 doi | |
| 050 | 4 | |a RS201.S6 |b S65 2020 | |
| 060 | 4 | |a QV 744 | |
| 072 | 7 | |a MED071000 |2 bisacsh | |
| 082 | 0 | 4 | |a 615.1/9 |2 23 |
| 049 | |a MAIN | ||
| 245 | 0 | 0 | |a Solubility in pharmaceutical chemistry |c edited by Christoph Saal, Anita Nair. |
| 264 | 1 | |a Berlin ; |a Boston |b Walter de Gruyter GmbH, |c [2020] | |
| 300 | |a 1 online resource | ||
| 347 | |a text file | ||
| 347 | |b PDF | ||
| 505 | 0 | 0 | |t Frontmatter -- |t Contents -- |t List of contributors -- |t 1. Solubility -- definition and basic physicochemical considerations / |r Elder, David -- |t 2. Solubility and supersaturation / |r Bauer-Brandl, Annette / Brandl, Martin -- |t 3. In Silico methods to predict solubility / |r McDonagh, James L. / Mitchell, John Bo / Palmer, David S / Skyner, Rachael E. -- |t 4. How solubility influences bioavailability / |r Faller, Bernard / Desrayaud, Sandrine / Berghausen, Joerg / Laisney, Marc / Dodd, Stephanie -- |t 5. Estimation of intraluminal drug solubility / |r Reppas, Christos / Vertzoni, Maria -- |t 6. Biorelevant media / |r Dressman, Jennifer -- |t 7. The role of solubility to optimize drug substances -- a medicinal chemistry perspective / |r Saal, Christoph / Valko, Klara -- |t 8. The role of solubility in optimizing drug products -- a pharmaceutical development perspective / |r Holm, René -- |t 9. The relevance of solid-state forms for solubility / |r Saal, Christoph -- |t 10. Solubility and phase behaviour from a drug substance manufacturing perspective / |r Beckmann, Wolfgang -- |t 11. Biowaivers / |r Elder, David -- |t List of Abbreviations -- |t Index |
| 520 | |a This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book. | ||
| 546 | |a In English. | ||
| 588 | 0 | |a Online resource; title from PDF title page (publisher's Web site, viewed 21. Dez 2019). | |
| 653 | 0 | |a Drugs |x Solubility. | |
| 653 | 0 | |a Pharmaceutical chemistry. | |
| 653 | 0 | |a Solubility. | |
| 653 | 0 | |a Drugs. | |
| 653 | 2 | |a Solubility | |
| 653 | 2 | |a Chemistry, Pharmaceutical | |
| 653 | 2 | |a Pharmaceutical Preparations | |
| 653 | 6 | |a Médicaments |x Solubilité. | |
| 653 | 6 | |a Chimie pharmaceutique. | |
| 653 | 6 | |a Solubilité. | |
| 653 | 6 | |a Médicaments. | |
| 653 | 7 | |a solubility. |2 aat | |
| 653 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 653 | 7 | |a Drugs |x Solubility |2 fast |0 (OCoLC)fst00898918 | |
| 653 | 7 | |a Pharmaceutical chemistry |2 fast |0 (OCoLC)fst01060115 | |
| 655 | 0 | |a EBSCO eBooks |9 905790 | |
| 655 | 4 | |a Electronic books. |9 899821 | |
| 700 | 1 | |a Saal, Christoph, |9 907053 | |
| 700 | 1 | |a Nair, Anita, |9 907054 | |
| 856 | 4 | 0 | |3 EBSCOhost |u https://www.lib.tsu.ru/limit/2023/EBSCO/2333427.pdf |
| 856 | |y Перейти в каталог НБ ТГУ |u https://koha.lib.tsu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=1011435 | ||
| 910 | |a EBSCO eBooks | ||
| 999 | |c 1011435 |d 1011435 | ||
| 039 | |||