Invasive and minimally invasive evaluation of diffusion properties of sugar in muscle

In this article, the use of diffuse reflectance (Rd) spectroscopy is explored to evaluate the diffusion properties of water and sucrose in skeletal muscle during optical clearing treatments. Treating muscle samples with sucrose-water solutions with different osmolarities, collimated transmittance (T...

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Опубликовано в: :IEEE journal of selected topics in quantum electronics Vol. 29, № 4. P. 7000508 (1-8)
Главный автор: Pinheiro, Maria Rosario
Другие авторы: Tuchin, Valery V., Oliveira, Luís Manuel
Формат: Статья в журнале
Язык:English
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Online-ссылка:http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001016726
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520 3 |a In this article, the use of diffuse reflectance (Rd) spectroscopy is explored to evaluate the diffusion properties of water and sucrose in skeletal muscle during optical clearing treatments. Treating muscle samples with sucrose-water solutions with different osmolarities, collimated transmittance (Tc) and Rd measurements were performed to obtain the diffusion time (τ) and the diffusion coefficient (D) values that characterize the unique water and sucrose fluxes in the muscle and also the optical clearing mechanisms designated as tissue dehydration and refractive index matching. Considering the Rd measurements, the estimated τ and D values for water in the muscle were 63.1s and 1.72×10-6 cm2/s, while the ones estimated for sucrose were 261s and 4.86×10-7 cm2/s. Comparing these values with the ones estimated from the Tc measurements, the relative differences observed for τ and D were 1.6% and 2.8% in the case of water and 0.3% and 0.4% in the case of sucrose. 
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700 1 |a Oliveira, Luís Manuel 
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