Association between maternal depression symptoms across the first eleven years of their child's life and subsequent offspring suicidal ideation

Depression is common, especially in women of child-bearing age; prevalence estimates for this group range from 8% to 12%, and there is robust evidence that maternal depression is associated with mental health problems in offspring. Suicidal behaviour is a growing concern amongst young people and tho...

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Опубликовано в: :PLoS ONE Vol. 10, № 7. P. e0131885 (1-18)
Главный автор: Hammerton, Gemma
Другие авторы: Mahedy, Liam, Mars, Becky, Harold, Gordon T., Thapar, Anita, Zammit, Stanley, Collishaw, Stephan
Формат: Статья в журнале
Язык:English
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Online-ссылка:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000625568
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024 7 |a 10.1371/journal.pone.0131885  |2 doi 
035 |a to000625568 
039 9 |a 201805070841  |c 201804241614  |d VLOAD  |y 201804241539  |z Александр Эльверович Гилязов 
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100 1 |a Hammerton, Gemma  |9 286131 
245 1 0 |a Association between maternal depression symptoms across the first eleven years of their child's life and subsequent offspring suicidal ideation  |c G. Hammerton, L. Mahedy, B. Mars [et.al.] 
504 |a Библиогр.: 45 назв. 
520 3 |a Depression is common, especially in women of child-bearing age; prevalence estimates for this group range from 8% to 12%, and there is robust evidence that maternal depression is associated with mental health problems in offspring. Suicidal behaviour is a growing concern amongst young people and those exposed to maternal depression are likely to be especially at high risk. The aim of this study was to utilise a large, prospective population cohort to examine the relationship between depression symptom trajectories in mothers over the first eleven years of their child's life and subsequent adolescent suicidal ideation. An additional aim was to test if associations were explained by maternal suicide attempt and offspring depressive disorder. Data were utilised from a population-based birth cohort: the Avon Longitudinal Study of Parents and Children. Maternal depression symptoms were assessed repeatedly from pregnancy to child age 11 years. Offspring suicidal ideation was assessed at age 16 years. Using multiple imputation, data for 10,559 families were analysed. Using latent class growth analysis, five distinct classes of maternal depression symptoms were identified (minimal, mild, increasing, sub-threshold, chronic-severe). The prevalence of past-year suicidal ideation at age 16 years was 15% (95% CI: 14-17%). Compared to offspring of mothers with minimal symptoms, the greatest risk of suicidal ideation was found for offspring of mothers with chronic-severe symptoms [OR 3.04 (95% CI 2.19, 4.21)], with evidence for smaller increases in risk of suicidal ideation in offspring of mothers with sub-threshold, increasing and mild symptoms. These associations were not fully accounted for by maternal suicide attempt or offspring depression diagnosis. Twenty-six percent of non-depressed offspring of mothers with chronic-severe depression symptoms reported suicidal ideation. Risk for suicidal ideation should be considered in young people whose mothers have a history of sustained high levels of depression symptoms, even when the offspring themselves do not have a depression diagnosis. 
653 |a депрессии 
653 |a суицидальное поведение 
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655 4 |a статьи в журналах  |9 879358 
700 1 |a Mahedy, Liam  |9 286132 
700 1 |a Mars, Becky  |9 286133 
700 1 |a Harold, Gordon T.  |9 286134 
700 1 |a Thapar, Anita  |9 286135 
700 1 |a Zammit, Stanley  |9 286136 
700 1 |a Collishaw, Stephan  |9 286137 
773 0 |t PLoS ONE  |d 2015  |g Vol. 10, № 7. P. e0131885 (1-18)  |x 1932-6203 
852 4 |a RU-ToGU 
856 7 |u http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000625568 
856 |y Перейти в каталог НБ ТГУ  |u https://koha.lib.tsu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=207425 
908 |a статья 
999 |c 207425  |d 207425