Heteroaromatic Lipoxin A4 Analogues Synthesis and Biological Evaluation /
In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines kno...
| Published in: | Springer eBooks |
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| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2012.
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| Series: | Springer Theses
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/978-3-642-24632-6 Перейти в каталог НБ ТГУ |
Table of Contents:
- Introduction
- Recent advances in the chemistry and biology of stable synthetic Lipoxin analogues
- Synthesis of Heck coupling partner for the preparation of heteroaromatic Lipoxin A4 analogues
- Synthesis and biological evaluation of pyridine-containing Lipoxin A4 analogues
- Thiophene-containing Lipoxin A4 analogues: synthesis and their effect on the production of key cytokines
- Towards the synthesis of various heteroaromatic Lipoxin A4 analogues.