Pharmaco-Imaging in Drug and Biologics Development Fundamentals and Applications /

Advances in drugs and biologics to mitigate or cure some of nature's most complex medical problems have been incredible to behold.  These accomplishments are due to the actions of a wide theatre of participants from biologists, pharmacologists, geneticists, chemists and manufacturers, molecular...

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Bibliographic Details
Published in:Springer eBooks
Corporate Author: SpringerLink (Online service)
Other Authors: Moyer, Brian R. (Editor), Cheruvu, Narayan P.S (Editor), Hu, Tom C.-C (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2014.
Series:AAPS Advances in the Pharmaceutical Sciences Series,
Subjects:
Online Access:http://dx.doi.org/10.1007/978-1-4614-8247-5
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Table of Contents:
  • Imaging Platforms and Drug Development:  An Introduction
  • Imaging in Drug Development: Animal Models, Handling and Physiological Constraints
  • Considerations for Pre-Clinical Laboratory Animal Imaging Center Design, Setup, and Management suitable for Biomedical Investigation for Drug Discovery
  • Pharmaco-Imaging in Translational Science and Research
  • The Role of Pharmacokinetics and Allometrics in Imaging: Practical Issues and Considerations
  • Quantitative Imaging Using Autoradiographic Techniques
  • Pre-Clinical Imaging in Oncology: Considerations and Recommendations for the Imaging Scientist
  • Use of Radiolabelled Leukocytes for Drug Evaluation in Man
  • Application of Bioluminescence Imaging (BLI) to the Study of the Animal Models of Human Infectious Diseases
  • Pre-Clinical Imaging in BSL-3 and BSL-4 Environments:  Imaging Pathophysiology of Highly Pathogenic Infectious Diseases
  • Magnetic Resonance as a Tool for Pharmaco-Imaging
  • Technologies and Principles of Mass Spectral Imaging
  • Regulatory Considerations Involved In Imaging.