Management of Castration Resistant Prostate Cancer
This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based the...
| Published in: | Springer eBooks |
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| Corporate Author: | |
| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Humana Press,
2014.
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| Series: | Current Clinical Urology,
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/978-1-4939-1176-9 Перейти в каталог НБ ТГУ |
Table of Contents:
- Introduction - Castration Resistant Prostate Cancer: A Rapidly Expanding Clinical State and a Model for New Therapeutic Opportunities
- Evolution of Clinical States and the Castration Resistant Clinical Paradigm
- Molecular Mechanisms of Prostate Cancer Progression after Castration
- New Imaging Modalities
- Androgen Receptor Biology in Castration Resistant Prostate Cancer
- The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer
- Approaches Targeting Androgen Synthesis (CYP 17 inhibitors)
- Cytotoxic Chemotherapy (Taxanes and Taxane Combinations)
- The Emerging Role of Immunotherapy in Castrate Resistant Prostate Cancer
- Bone Targeted Therapy: Rationale and Current Status
- Radium-223 and Other Radiopharmaceuticals in Prostate Cancer
- Introduction
- Phase I/II targeted treatments
- Defining Clinical Endpoints in Castration-resistant Prostate Cancer
- Angiogenesis Inhibition in Castration Resistant Prostate Cancer
- Co-targeting Adaptive Survival Pathways
- Targeting the PI3K/AKT/mTOR Pathway in Prostate Cancer
- PARP Inhibitors
- Targeting C-Met/VEGF in Castration Resistant Prostate Cancer
- Epigenetics in Castration Resistant Prostate Cancer
- Undifferentiated Prostate Cancer and the Neuroendocrine Phenotype
- Strategies Addressing Quality of Life: Patient Reported Outcome and Symptoms Management
- Evidence-Based Therapeutic Approaches for mCRPC patients: Rational Sequence of Standard Treatment Options and Design for Future Drug Development.