Modelling the Short QT Syndrome Gene Mutations And Their Role in Cardiac Arrhythmogenesis /
The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death. Although several gene mutations have been identified in SQT patients, the role of these mutations in promoting arrhythmogenesis is still not com...
| Published in: | Springer eBooks |
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| Format: | eBook |
| Language: | English |
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Cham :
Springer International Publishing : Imprint: Springer,
2014.
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| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/978-3-319-07200-5 Перейти в каталог НБ ТГУ |
Table of Contents:
- Ion Channels and the Action Potential
- Potassium Channels Implicated in the Short QT Syndrome
- The Short QT Syndrome
- Model Development
- Methods, Experimental Protocols and Mathematical Preliminaries
- Increased Vulnerability of the Human Ventricle to Re-entrant Excitation in HERG-linked SQT1
- Mathematically Modelling the Functional Consequences of the SQT2 Mutation
- Proarrhythmia in KCNJ2-linked Short QT Syndrome: Insights from Modelling
- Relationship between Electrical and Mechanical Systole in the Short QT Syndrome: Insights from Modelling
- Discussion and Conclusion.