Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials

Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials

This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identifie...

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Bibliographic Details
Published in:Springer eBooks
Main Authors: Kiang, Tony K.L (Author), Wilby, Kyle John (Author), Ensom, Mary H.H (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Adis, 2015.
Subjects:
medicine.
Health promotion.
Tropical medicine.
Pharmacy.
Medicine & Public Health.
Tropical Medicine.
Health Promotion and Disease Prevention.
Drug Safety and Pharmacovigilance.
Online Access:http://dx.doi.org/10.1007/978-3-319-10527-7
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Table of Contents:
  • Introduction
  • Pharmacology of Recommended Antimalarial Agents
  • Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials
  • Pharmacokinetic Drug Interactions Affecting Antimalarials
  • Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs
  • Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials
  • Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions
  • Limitations, Future Directions, and Conclusions.

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