Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases
This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative disease...
| Published in: | Springer eBooks |
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| Corporate Author: | |
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Series: | Advances in Experimental Medicine and Biology,
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/978-3-319-18365-7 Перейти в каталог НБ ТГУ |
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| 245 | 1 | 0 | |a Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases |h electronic resource |c edited by Neville Vassallo. |
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| 490 | 1 | |a Advances in Experimental Medicine and Biology, |x 0065-2598 ; |v 863 | |
| 505 | 0 | |a Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer's disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson's disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. | |
| 520 | |a This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry. | ||
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