Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer
This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein-protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be nove...
| Опубликовано в: : | Springer eBooks |
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| Главный автор: | |
| Соавтор: | |
| Формат: | Электронная книга |
| Язык: | English |
| Публикация: |
Tokyo :
Springer Japan : Imprint: Springer,
2015.
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| Серии: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Предметы: | |
| Online-ссылка: | http://dx.doi.org/10.1007/978-4-431-55447-9 Перейти в каталог НБ ТГУ |
Оглавление:
- Introduction
- Total Synthesis of Thielocin B1 and NMR Chemical Shift Perturbation Experiments with PAC3 Homodimer
- Synthesis of Spin-labeled Thielocin B1 and Observation of Paramagnetic Relaxation Enhancement Effects
- An Improved Method for the Direct Formylation ob Substituted Benzenes Using Dichloromethyl Methyl Ether-Silver Trifluoromethanesulfonate
- Conclusions.