Effect of silver additive on physicochemical properties of hydroxyapatite applied to reconstructive surgery
The effect of silver adding to hydroxyapatite (HA) in its solubility in physiological solution and biological activity was investigated. Samples of HA containing silver (AgHA) obtained by liquid-phase method in the conditions of microwave exposure. Solubility (CCa2+·103, mol/l) of the powders AgHA w...
Published in: | AIP Conference Proceedings Vol. 1688. P. 060003-1-060003-6 |
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Main Author: | |
Other Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000578435 Перейти в каталог НБ ТГУ |
Summary: | The effect of silver adding to hydroxyapatite (HA) in its solubility in physiological solution and biological activity was investigated. Samples of HA containing silver (AgHA) obtained by liquid-phase method in the conditions of microwave exposure. Solubility (CCa2+·103, mol/l) of the powders AgHA was determined by chemical methods according trilonometric titration of the calcium ions in physiological solution at 25 and 37 °C. To investigate the biological activity of the samples, a series of experiments on the formation of the calcium-phosphate layer on the surface of the SBF-solution at 37 °C for 28 days. Electronic micrographs of samples taken at the end of each 7 days of the experiment, indicate the formation of calcium-phosphate layer (CPL) in the samples, the kinetics of which is shown as a function of cumulative concentrations of calcium and magnesium ions from time. |
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Bibliography: | Библиогр.: 20 назв. |
ISSN: | 0094-243X |