Shape-dependent interaction of gold nanoparticles with cultured cells at laser exposure

Laser optoporation of cells by local heating of plasmonic gold nanoparticles (GNPs) was proven as a favorable delivery method of molecules into cells. The optoporation efficiency depends on the laser beam intensity and GNP properties. Here, we evaluate the membrane optoporation in vitro in terms of...

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Bibliographic Details
Published in:Laser physics letters Vol. 14, № 5. P. 055901 (1-5)
Other Authors: Bibikova, Olga, Popov, Alexey P, Akchurin, Garif G., Skaptsov, A., Skovorodkin, I., Khanadeev, V., Mikhalevich, D., Kinnunen, M., Singh, P., Bogatyrev, Vladimir A., Khlebtsov, Nikolay G., Vainio, S. J., Meglinski, Igor V., Tuchin, Valery V.
Format: Article
Language:English
Subjects:
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000618343
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245 1 0 |a Shape-dependent interaction of gold nanoparticles with cultured cells at laser exposure  |c O. Bibikova, P. Singh, A. Popov [et.al.] 
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520 3 |a Laser optoporation of cells by local heating of plasmonic gold nanoparticles (GNPs) was proven as a favorable delivery method of molecules into cells. The optoporation efficiency depends on the laser beam intensity and GNP properties. Here, we evaluate the membrane optoporation in vitro in terms of fluorescent dye permeability under treatment of a multi-pulsed nanosecond 1064 nm laser with a sharply-focused beam. Anisotropic GNPs, such as nanorods and nanostars, were fabricated to achieve the optimal GNP-cell interaction. Nanostars demonstrated highest optoporation efficacy with more than 80% of permeabilized cells within the illuminated area. By contrast to common laser techniques, the laser beam scanning method results in cell optoporation within a controllable programmed in advance irradiated area. 
653 |a наночастицы золота 
653 |a воздействие лазерного излучения 
653 |a оплодотворение клетки 
655 4 |a статьи в журналах  |9 879358 
700 1 |a Bibikova, Olga  |9 478695 
700 1 |a Popov, Alexey P  |9 113424 
700 1 |a Akchurin, Garif G.  |9 508565 
700 1 |a Skaptsov, A.  |9 479265 
700 1 |a Skovorodkin, I.  |9 479266 
700 1 |a Khanadeev, V.  |9 479267 
700 1 |a Mikhalevich, D.  |9 479268 
700 1 |a Kinnunen, M.  |9 478697 
700 1 |a Singh, P.  |9 479269 
700 1 |a Bogatyrev, Vladimir A.  |9 135353 
700 1 |a Khlebtsov, Nikolay G.  |9 106606 
700 1 |a Vainio, S. J.  |9 479270 
700 1 |a Meglinski, Igor V.  |9 111386 
700 1 |a Tuchin, Valery V.  |9 78712 
773 0 |t Laser physics letters  |d 2017  |g Vol. 14, № 5. P. 055901 (1-5)  |x 1612-2011 
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