Morphology alterations of skin and subcutaneous fat at NIR laser irradiation combined with delivery of encapsulated indocyanine green
The goal of this study is to quantify the impact of the in vivo photochemical treatment of rats with obesity using indocyanine green (ICG) dissolved in saline or dispersed in an encapsulated form at NIR laser irradiation, which was monitored by tissue sampling and histochemistry. The subcutaneous in...
| Published in: | Journal of biomedical optics Vol. 22, № 5. P. 055008-1-055008-7 |
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| Other Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000620248 Перейти в каталог НБ ТГУ |
| LEADER | 02806nab a2200385 c 4500 | ||
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| 008 | 180126|2017 xxu s a eng d | ||
| 024 | 7 | |a 10.1117/1.JBO.22.5.055008 |2 doi | |
| 035 | |a to000620248 | ||
| 039 | 9 | |a 201801290924 |b 100 |c 201801261554 |d VLOAD |y 201801261547 |z Александр Эльверович Гилязов | |
| 040 | |a RU-ToGU |b rus |c RU-ToGU | ||
| 245 | 1 | 0 | |a Morphology alterations of skin and subcutaneous fat at NIR laser irradiation combined with delivery of encapsulated indocyanine green |c I. Y. Yanina, N. A. Navolokin, Y. I. Svenskaya [et.al.] |
| 504 | |a Библиогр.: 76 назв. | ||
| 520 | 3 | |a The goal of this study is to quantify the impact of the in vivo photochemical treatment of rats with obesity using indocyanine green (ICG) dissolved in saline or dispersed in an encapsulated form at NIR laser irradiation, which was monitored by tissue sampling and histochemistry. The subcutaneous injection of the ICG solution or ICG encapsulated into polyelectrolyte microcapsules, followed by diode laser irradiation (808 nm, 8 W / cm 2 , 1 min), resulted in substantial differences in lipolysis of subcutaneous fat. Most of the morphology alterations occurred in response to the laser irradiation if a free-ICG solution had been injected. In such conditions, membrane disruption, stretching, and even delamination in some cases were observed for a number of cells. The encapsulated ICG aroused similar morphology changes but with weakly expressed adipocyte destruction under the laser irradiation. The Cochran Q test rendered the difference between the treatment alternatives statistically significant. By this means, laser treatment using the encapsulated form of ICG seems more promising and could be used for safe layerwise laser treatment of obesity and cellulite | |
| 653 | |a жировая ткань | ||
| 653 | |a гистологический анализ | ||
| 653 | |a липолиз | ||
| 655 | 4 | |a статьи в журналах |9 879358 | |
| 700 | 1 | |a Yanina, Irina Yu. |9 113429 | |
| 700 | 1 | |a Svenskaya, Yulia I. |9 345268 | |
| 700 | 1 | |a Bucharskaya, Alla B. |9 113426 | |
| 700 | 1 | |a Maslyakova, Galina N. |9 135349 | |
| 700 | 1 | |a Gorin, Dmitry A. |9 345267 | |
| 700 | 1 | |a Sukhorukov, Gleb B. |9 113431 | |
| 700 | 1 | |a Tuchin, Valery V. |9 78712 | |
| 700 | 1 | |a Navolokin, Nikita A. |9 113427 | |
| 773 | 0 | |t Journal of biomedical optics |d 2017 |g Vol. 22, № 5. P. 055008-1-055008-7 |x 1083-3668 | |
| 852 | 4 | |a RU-ToGU | |
| 856 | 7 | |u http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000620248 | |
| 856 | |y Перейти в каталог НБ ТГУ |u https://koha.lib.tsu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=431105 | ||
| 908 | |a статья | ||
| 999 | |c 431105 |d 431105 | ||