Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy

Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy

Purpose High activity of enzyme TOP2a in tumor cells is known to be associated with sensitivity to anthracycline chemotherapy, but 20% of such patients do not show clinical response. Tumor microenvironment, including tumor-associated macrophages (TAM), is an essential factor defining the efficiency...

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Bibliographic Details
Published in:Cancer chemotherapy and pharmacology Vol. 82, № 1. P. 99-109
Other Authors: Tsyganov, Matvey M., Larionova, Irina V, Ibragimova, Marina K., Deryusheva, Irina V., Kazantseva, Polina V., Slonimskaya, Elena M., Frolova, Irina G., Choinzonov, Evgeny L., Cherdyntseva, Nadezhda V., Litvyakov, Nicolay V., Kzhyshkowska, Julia G.
Format: Article
Language:English
Subjects:
рак молочной железы
неоадъювантная химиотерапия
макрофаги
доксорубицин
статьи в журналах
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000634057
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