The laser technologies of targeted opening of blood-brain barrier for drug brain delivery

The laser technologies of targeted opening of blood-brain barrier for drug brain delivery

Here we show the photodynamic treatment (PDT) causes significant increase in the permeability of the blood-brain barrier (BBB) in healthy mice. Using different doses of laser (635 nm, 10-40 J/cm2) and photosensitizer (5- aminole-vulinic acid - 5-ALA, 20 and 80 mg/kg, i.v.), we found the optimal...

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Bibliographic Details
Published in:International Conference Laser Optics 2018 (ICLO 2018), St. Petersburg, Russia, 4-8 June, 2018 : proceedings P. 501
Other Authors: Rafailov, E. U., Sokolovsky, S. G., Borisova, Ekaterina G., Mantareva, Vanya, Angelov, Ivan, Shirokov, Alexander, Navolokin, Nikita A., Shushunova, Natalia A., Khorovodov, Alexander P., Semyachkina-Glushkovskaya, Oxana V., Terskov, Andrey V., Bodrova, Anastasia A., Ulanova, Mariya V, Shrif, Esmat, Tuchin, Valery V., Kurths, Jürgen
Format: Book Chapter
Language:English
Subjects:
гематоэнцефалический барьер
лазерные технологии
фотодинамическая терапия
статьи в сборниках
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000659761
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