Research and development of effective optical technologies for diagnostics in dermatology

Optical clearing of the human skin under the action of hyaluronic acid (HA) as an enhancer for optical clearing by polyethylene glycol (PEG-300) was studied in vivo by optical coherent tomography (OCT) method on the wavelength 930±5 nm. The results have showed an increase in the transparency of the...

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Published in:Proceedings of SPIE Vol. 11065 : Saratov fall meeting 2018 : Optical and nano-technologies for biology and medicine. P. 1106505-1-1106505-8
Other Authors: Genin, Vadim D., Rakotomanga, Prisca, Zaytsev, Sergey M., Genina, Elina A., Lazareva, Ekaterina N., Khairallah, Grégoire, Amouroux, Marine, Soussen, Charles, Chen, Hang, Feng, Wei, Zhu, Dan, Bashkatov, Alexey N., Blondel, Walter, Tuchin, Valery V.
Format: Article
Language:English
Subjects:
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000565132
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245 1 0 |a Research and development of effective optical technologies for diagnostics in dermatology  |c V. D. Genin, P. Rakotomanga, D. Zhu [et al.] 
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520 3 |a Optical clearing of the human skin under the action of hyaluronic acid (HA) as an enhancer for optical clearing by polyethylene glycol (PEG-300) was studied in vivo by optical coherent tomography (OCT) method on the wavelength 930±5 nm. The results have showed an increase in the transparency of the epidermis at the optical depth of 50±5 μm by 44±9% within 15 min with the use of a solution of HA in combination with sonophoresis before application of PEG-300 to the skin surface. At the same time, when using PEG-300 without preliminary treatment of the skin with the HA, an increase in the transparency of the epidermis at the same depth was 21±8% within 25 min. In dermis at the depth of 500 μm the OCT signal in the experimental group increased more than 1.6 fold what indicates an increasing of optical probing depth. 
653 |a кожа человека 
653 |a гиалуроновая кислота 
653 |a энхансер 
653 |a сонофорез 
653 |a оптическая когерентная томография 
655 4 |a статьи в журналах  |9 879358 
700 1 |a Genin, Vadim D.  |9 504588 
700 1 |a Rakotomanga, Prisca  |9 498951 
700 1 |a Zaytsev, Sergey M.  |9 508175 
700 1 |a Genina, Elina A.  |9 113421 
700 1 |a Lazareva, Ekaterina N.  |9 484140 
700 1 |a Khairallah, Grégoire  |9 498945 
700 1 |a Amouroux, Marine  |9 498946 
700 1 |a Soussen, Charles  |9 498944 
700 1 |a Chen, Hang  |9 498948 
700 1 |a Feng, Wei  |9 563602 
700 1 |a Zhu, Dan  |9 471539 
700 1 |a Bashkatov, Alexey N.  |9 113422 
700 1 |a Blondel, Walter  |9 498952 
700 1 |a Tuchin, Valery V.  |9 78712 
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