Antibacterial ferroelectric hybrid membranes fabricated via electrospinning for wound healing

n the present study, wound healing ferroelectric membranes doped with zinc oxide nanoparticles were fabricated from vinylidene fluoride-tetrafluoroethylene copolymer and polyvinylpyrrolidone using the electrospinning technique. Five different ratios of vinylidene fluoride-tetrafluoroethylene to poly...

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Bibliographic Details
Published in:Membranes Vol. 11, № 12. P. 986 (1-14)
Other Authors: Lukiev, Ivan V., Antipina, Ludmila S., Goreninskii, Semen I., Tverdokhlebova, Tamara S., Vasilchenko, Dmitry V., Nemoykina, Anna L., Goncharova, Darya A., Svetlichnyi, Valerii A., Dambaev, Georgiy Ts, Bouznik, Vyacheslav M., Bolbasov, Evgeny N.
Format: Article
Language:English
Subjects:
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000897488
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245 1 0 |a Antibacterial ferroelectric hybrid membranes fabricated via electrospinning for wound healing  |c I. V. Lukiev, L. S. Antipina, S. I. Goreninskii [et al.] 
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520 3 |a n the present study, wound healing ferroelectric membranes doped with zinc oxide nanoparticles were fabricated from vinylidene fluoride-tetrafluoroethylene copolymer and polyvinylpyrrolidone using the electrospinning technique. Five different ratios of vinylidene fluoride-tetrafluoroethylene to polyvinylpyrrolidone were used to control the properties of the membranes at a constant zinc oxide nanoparticle content. It was found that an increase of polyvinylpyrrolidone content leads to a decrease of the spinning solution conductivity and viscosity, causing a decrease of the average fiber diameter and reducing their strength and elongation. By means of X-ray diffraction and infrared spectroscopy, it was revealed that increased polyvinylpyrrolidone content leads to difficulty in crystallization of the vinylidene fluoride-tetrafluoroethylene copolymer in the ferroelectric β-phase in membranes. Changing the ratio of vinylidene fluoride-tetrafluoroethylene copolymer and polyvinylpyrrolidone with a constant content of zinc oxide nanoparticles is an effective approach to control the antibacterial properties of membranes towards Staphylococcus aureus. After carrying out in vivo experiments, we found that ferroelectric hybrid membranes, containing from five to ten mass percent of PVP, have the greatest wound-healing effect for the healing of purulent wounds 
653 |a сегнетоэлектрики 
653 |a электропрядение 
653 |a нановолокна 
653 |a заживление ран 
655 4 |a статьи в журналах  |9 879358 
700 1 |a Lukiev, Ivan V.  |9 809055 
700 1 |a Antipina, Ludmila S.  |9 809057 
700 1 |a Goreninskii, Semen I.  |9 480251 
700 1 |a Tverdokhlebova, Tamara S.  |9 809058 
700 1 |a Vasilchenko, Dmitry V.  |9 809059 
700 1 |a Nemoykina, Anna L.  |9 46252 
700 1 |a Goncharova, Darya A.  |9 346755 
700 1 |a Svetlichnyi, Valerii A.  |9 562988 
700 1 |a Dambaev, Georgiy Ts.  |9 148278 
700 1 |a Bouznik, Vyacheslav M.  |9 809060 
700 1 |a Bolbasov, Evgeny N.  |9 92075 
773 0 |t Membranes  |d 2021  |g Vol. 11, № 12. P. 986 (1-14)  |x 2077-0375 
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