Phosphorylation of Na+,K+‑ATPase at Tyr10 of the α1‑subunit is suppressed by AMPK and enhanced by ouabain in cultured kidney cells
Na+,K+-ATPase (NKA) is essential for maintenance of cellular and whole-body water and ion homeostasis. In the kidney, a major site of ion transport, NKA consumes ~ 50% of ATP, indicating a tight coordination of NKA and energy metabolism. AMP-activated protein kinase (AMPK), a cellular energy sensor,...
| Published in: | The Journal of membrane biology Vol. 254, № 5/6. P. 531-548 |
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| Other Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000897588 Перейти в каталог НБ ТГУ |