Optical clearing of tissues: Issues of antimicrobial phototherapy and drug delivery
In the modern world, with a poor environmental situation, there is a certain ''erasure" of the boundaries between pathogenic, opportunistic microorganisms and commensals, the number of antibiotic-resistant bacterial strains is growing. The microbiome of the human body is made up of mo...
| Published in: | Advanced drug delivery reviews Vol. 180. P. 114037 (1-35) |
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| Other Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000927122 Перейти в каталог НБ ТГУ |
| Summary: | In the modern world, with a poor environmental situation, there is a certain ''erasure" of the boundaries between pathogenic, opportunistic microorganisms and commensals, the number of antibiotic-resistant bacterial strains is growing. The microbiome of the human body is made up of more than 500 types of microorganisms, representing an integral ecological system, which is in a state of dynamic equilibriumwith macroorganism. Colonization of various biotopes is carried out by the formation of a biofilm, which represents several layers of microorganisms covered with a common glycocalyx and enclosed in a highly hydrated exopolysaccharide-mucin matrix. Under certain conditions, opportunistic bacteria can become causative agents of purulentinflammatory diseases, i.e. the mechanism of autoinfection is realized with a decrease in the body's resistance or their translocation into unusual biotopes. |
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| Bibliography: | Библиогр.: 468 назв. |
| ISSN: | 0169-409X |