Determination of BRCAness phenotype in breast tumors for the appointment of neoadjuvant chemotherapy based on platinum and taxanes

The concept of BRCAness was developed because of similarities between sporadic and hereditary breast cancer. BRCAness defines the pathogenesis and treatment sensitivity of many types of cancer, as well as the presence of a defect in the homologous recombination repair of tumor cells simulating the l...

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Bibliographic Details

Published in:	International journal of molecular sciences Vol. 24, № 1. P. 207 (1-13)
Other Authors:	Tsyganov, Matvey M., Ibragimova, Marina K., Garbukov, Evgeny Yu, Bragina, Olga D., Karchevskaya, Ariana A., Usynin, Evgeny A., Litvyakov, Nicolay V.
Format:	Article
Language:	English
Subjects:	рак молочной железы аберрации числа копий ДНК экспрессия генов гомологичная рекомбинация дефицит гомологичной рекомбинации потеря гетерозиготности микроматричный анализ неоадъювантная химиотерапия индивидуальное лечение BRCA-мутации статьи в журналах
Online Access:	http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:001009372 Перейти в каталог НБ ТГУ