Cardioprotective effects of a selective c-Jun N-terminal kinase inhibitor in a rat model of myocardial infarction

Cardioprotective effects of a selective c-Jun N-terminal kinase inhibitor in a rat model of myocardial infarction

Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was to evaluate the effects of a selective JNK inhibitor, 11H-indeno [1,2-b]quinoxalin-11-one oxime (IQ-...

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Bibliographic Details
Published in:Biomedicines Vol. 11, № 3. P. 714 (1-15)
Other Authors: Plotnikov, Mark B., Chernysheva, Galina A., Smolyakova, Vera I., Aliev, Oleg I., Fomina, Tatyana I., Sandrikina, Lyubov A., Sukhodolo, Irina V., Ivanova, Vera V., Osipenko, Anton N., Anfinogenova, Nina D., Khlebnikov, Andrei I., Atochin, Dmitriy N., Schepetkin, Igor A., Quinn, Mark T.
Format: Article
Language:English
Subjects:
кардиопротекторная активность
ингибитор JNK
11H-индено[1,2-b]хиноксалин-11
сердечная недостаточность
инфаркт миокарда
реперфузия
ишемия
статьи в журналах
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