Electrical pulse stimulation decreases electrochemical Na+ and K+ gradients in C2C12 myotubes

Electrical pulse stimulation (EPS)-treated cultured myotubes are widely employed as an in vitro model of muscle contraction. Here we examined time-dependent EPS action and dose-dependent ouabain action on [Na+]i and [K+]i in C2C12 myotubes. After 2 h of EPS (40 V, 1 Hz, 10 ms) [Na+]i increased by ∼1...

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Bibliographic Details
Published in:Biochemical and biophysical research communications Vol. 493, № 2. P. 875-878
Other Authors: Danilov, Kirill, Milovanova, Kseniya G., Klimanova, Elizaveta A., Kapilevich, Leonid V. 1963-, Orlov, Sergei N., Sidorenko, Svetlana V.
Format: Article
Language:English
Subjects:
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000620694
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