Nitro-imidazoles in ferrocenyl alkylation reaction. Synthesis, enantiomeric resolution and in vitro and in vivo bioeffects

Ferrocenylalkyl nitro-imidazoles (4a-h, 5a-h) were prepared via the regiospecific reaction of the α-(hydroxy)alkyl ferrocenes, FcCHR (OH) (1a-h; Fc = ferrocenyl; R = H, Me, Et, Pr, i-Pr, Ph, ortho-Cl-Ph, ortho-I-Ph), with nitro-imidazoles in aqueous organic medium (H2O-CH2Cl2) at room temperature in...

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Опубликовано в: :Journal of Organometallic Chemistry Vol. 871. P. 10-20
Другие авторы: Lyapunova, Maria V., Verina, Daria D., Kachala, Vadim V., Korlyukov, Alexander A., Ilyin, Mikhail M., Davankov, Vadim A., Ostrovskaya, Larissa A., Bluchterova, Natalia V., Fomina, Margarita M., Snegur, Lubov V., Malkov, Victor S., Nevskaya, Kseniya V., Pershina, Alexandra G., Simenel, Alexander A.
Формат: Статья в журнале
Язык:English
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Online-ссылка:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000790019
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