Nitro-imidazoles in ferrocenyl alkylation reaction. Synthesis, enantiomeric resolution and in vitro and in vivo bioeffects

Nitro-imidazoles in ferrocenyl alkylation reaction. Synthesis, enantiomeric resolution and in vitro and in vivo bioeffects

Ferrocenylalkyl nitro-imidazoles (4a-h, 5a-h) were prepared via the regiospecific reaction of the α-(hydroxy)alkyl ferrocenes, FcCHR (OH) (1a-h; Fc = ferrocenyl; R = H, Me, Et, Pr, i-Pr, Ph, ortho-Cl-Ph, ortho-I-Ph), with nitro-imidazoles in aqueous organic medium (H2O-CH2Cl2) at room temperature in...

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Bibliographic Details
Published in:Journal of Organometallic Chemistry Vol. 871. P. 10-20
Other Authors: Lyapunova, Maria V., Verina, Daria D., Kachala, Vadim V., Korlyukov, Alexander A., Ilyin, Mikhail M., Davankov, Vadim A., Ostrovskaya, Larissa A., Bluchterova, Natalia V., Fomina, Margarita M., Snegur, Lubov V., Malkov, Victor S., Nevskaya, Kseniya V., Pershina, Alexandra G., Simenel, Alexander A.
Format: Article
Language:English
Subjects:
ферроценовые соединения
нитроимидазолы
статьи в журналах
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000790019
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