NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice

Skeletal muscle from mdx mice is characterized by increased Nox2 ROS, altered microtubule network, increased muscle stiffness, and decreased muscle/respiratory function. While microtubule de-tyrosination has been suggested to increase stiffness and Nox2 ROS production in isolated single myofibers, i...

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Bibliographic Details
Published in:eLife Vol. 7. P. e31732 (1-19)
Other Authors: Loehr, James Anthony, Cully, Tanya R., Pal, Rituraj, Larina, Irina V., Larin, Kirill V., Rodney, George G., Wang, Shang
Format: Article
Language:English
Subjects:
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000628506
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