Reprogrammed CD8+ T-lymphocytes isolated from bone marrow have anticancer potential in lung cancer

Reprogrammed CD8+ T-lymphocytes isolated from bone marrow have anticancer potential in lung cancer

CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes largely limits the effectiveness of therapy. In this study, reprogrammed T-lymphocytes used MEK inhibi...

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Bibliographic Details
Published in:Biomedicines Vol. 10, № 6. P. 1450 (1-18)
Other Authors: Skurikhin, Evgenii G., Pershina, Olga, Ermakova, Natalia N., Pakhomova, Angelina, Widera, Darius, Zhukova, Mariia, Pan, Edgar S., Sandrikina, Lyubov A., Kogai, Lena, Kushlinskii, Nikolai, Morozov, Sergey G., Kubatiev, Aslan A., Dygai, Alexander M.
Format: Article
Language:English
Subjects:
Льюиса карцинома легкого
иммунотерапия рака
MEK-ингибиторы
статьи в журналах
Online Access:http://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000923958
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